I haven’t done it but there is no reason why not, you just need to make regular calls to the lv_task_handler() and lv_tick_inc().
As for getting is working on the PC simulation, again possible, if there is already a Windows port of MicroOS then it should be very easy. If not, you’ll have to do quite a bit of work to port all the system calls to use Windows (i.e for threads, timers, etc)