Hello,
To drive such LED panels, we have to use the LTDC peripheral of the STM32, its available in STM32F429xx/STM32F469xx MCUs. Also you need to have adequate amount of RAM in the system. You need about 1125KB of RAM just for video buffer. If you double buffer then you need 2250KB. This much RAM is not available in your MCU. So the only option is to go for external SDRAM. Luckily, these MCU have an SDRAM controller built in. So you can easily hookup a SDRAM. But you need a good hardware designer to design PCB for SDRAM interface.
Further, these LCDs are NOT interfaced to GPIO but to LTDC.